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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB2
All Species:
40.3
Human Site:
T366
Identified Species:
63.33
UniProt:
Q9UBS0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBS0
NP_003943.2
482
53483
T366
D
T
R
F
T
R
Q
T
P
V
D
S
P
D
D
Chimpanzee
Pan troglodytes
XP_001172909
482
53404
T366
D
T
R
F
T
R
Q
T
P
V
D
S
P
D
D
Rhesus Macaque
Macaca mulatta
XP_001117937
512
56562
T393
D
T
R
F
T
R
Q
T
P
V
D
S
P
D
D
Dog
Lupus familis
XP_851971
482
53401
T364
D
T
H
F
T
R
Q
T
P
V
D
S
P
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M4
485
53520
T366
D
A
R
F
T
R
Q
T
P
V
D
S
P
D
D
Rat
Rattus norvegicus
P67999
525
59113
T390
D
S
K
F
T
R
Q
T
P
V
D
S
P
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
T347
D
S
K
F
T
R
Q
T
P
V
D
S
P
D
D
Chicken
Gallus gallus
P18652
752
84421
T377
D
T
E
F
T
S
R
T
P
K
D
S
P
G
I
Frog
Xenopus laevis
P10665
733
82620
T359
D
T
E
F
T
S
R
T
P
K
D
S
P
G
I
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
K363
F
D
P
E
F
T
A
K
T
P
K
D
S
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
P997
Y
G
F
D
E
N
A
P
P
L
P
L
P
E
E
Honey Bee
Apis mellifera
XP_395876
456
51514
R341
N
W
N
D
V
I
S
R
K
L
E
P
P
F
R
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
T401
D
P
E
F
T
K
R
T
P
K
D
S
P
A
L
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
T371
D
S
K
F
T
K
Q
T
P
V
D
S
P
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
L355
I
V
K
D
K
I
K
L
P
Q
F
L
S
N
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
91.8
95
N.A.
92.9
65.7
N.A.
70.9
30
30.5
30.2
N.A.
21.1
56.8
29.9
60.9
Protein Similarity:
100
99.7
92.5
96.6
N.A.
95
76
N.A.
80.9
42.8
42.5
43.2
N.A.
28.3
70.7
43.1
74.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
86.6
60
60
0
N.A.
13.3
6.6
53.3
80
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
100
66.6
66.6
0
N.A.
33.3
26.6
66.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
14
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
74
7
0
20
0
0
0
0
0
0
74
7
0
54
54
% D
% Glu:
0
0
20
7
7
0
0
0
0
0
7
0
0
7
14
% E
% Phe:
7
0
7
74
7
0
0
0
0
0
7
0
0
7
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
0
14
7
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
14
0
0
0
0
0
0
0
0
14
% I
% Lys:
0
0
27
0
7
14
7
7
7
20
7
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
7
0
14
0
14
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
0
7
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
7
7
0
0
0
0
7
87
7
7
7
87
7
0
% P
% Gln:
0
0
0
0
0
0
54
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
27
0
0
47
20
7
0
0
0
0
0
0
7
% R
% Ser:
0
20
0
0
0
14
7
0
0
0
0
74
14
0
0
% S
% Thr:
0
40
0
0
74
7
0
74
7
0
0
0
0
0
0
% T
% Val:
0
7
0
0
7
0
0
0
0
54
0
0
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _